Let’s face it, looking fab on the outside does not necessarily reflect what’s going on inside. If improving healthy longevity is a resolution for 2017, then invest in what matters by leveraging scientific innovation through preventive screening. By knowing where you stand in terms of the complex internal workings of your body, your anti-ageing physician will understand what to address, if change is necessary.

Once the health map is presented, the patient is given the power that comes with knowledge. To then embark on your journey towards optimal health, the patient must ensure that the health screening program does not stop with the presentation of their testing results, but rather begins there.
Dr. Graham Simpson, Chief Medical Officer and Co-Founder of Eternity Medicine Institute

When Do We Start?

The big question is when should we start preventive screenings? The forties, suggests Sam Rao, Director at XY Clinics and CEO at Diagnostika Molecular Labs, is often the starting point as various hormonal and metabolic changes become noticeable, and not surprisingly, chronic diseases, which are several years in the making, begin to show their symptoms by then. However, Dr. Sanjida Ahmed, Ph.D adds that individuals having a strong family history of any genetic conditions should take precautionary measures earlier than that. Yet there are some tests which should ideally be done when we are our healthiest.

If metabolic testing as well as a neurotransmitter panel is tested yearly, many behavioural, focus, mood and sleep issues can be avoided, whereby an improvement in memory and focus can be achieved.
– Guillaume Safah, Canadian Registered Clinical Nutritionist Consultant and CEO at The Anti-ageing Compounding Pharmacy

Predictions

One of the most important takeaways is that advances in health screening over the past decades now allow us to spot health conditions years in advance, asserts Dr. Graham. “For example, this year you may have a perfect calcium score of zero, the following year a calcium score of 30, and the year after that a calcium score of 100; what is causing this rapid progression towards coronary heart disease?” he asks and subsequently, what can be done to reverse it?

For many people, the first sign of coronary heart disease is sudden death and for this as well as many other life-threatening or life-altering illnesses, early detection is the only hope.
Dr. Graham Simpson, Chief Medical Officer and Co-Founder of Eternity Medicine Institute

What We All Should Be Doing

The most basic tests, claims Rao, are fasting blood sugar, insulin, vitamin D, cholesterol fractions, appetite control related markers, saliva hormones, and coeliac disease which can be done annually. However, as 90 percent of the tests that people are asked to do routinely can only tell if a person has a disease or illness symptom right now, Rao suggests more complex and advanced tests. Dr. Ahmed further adds that in addition to other tests such as blood pressure screening, heart disease prevention, colon cancer screening, and osteoporosis screening, there should be a preventive health visit every two years until age 50, and then once a year.

The Most Important

Cardiovascular

Yet overall, Rao urges that the single most important screening that should be done is for advanced cardiovascular risk simply because all routine tests fail to identify individuals who suffer from sudden heart attacks and stroke. “You can imagine how insufficient the current routine screening is if 50 percent of heart attacks and stroke events are taking place in individuals with normal or just borderline high cholesterol, and no other traditional risk factors,” he tells therefore undergoing these kinds of advanced tests which includes a genetically inherited risk can actually be life-saving. Brain health is as important and according to Safah, a neurotransmitter panel that allows for an indication of brain health. “Since the brain must direct the excretion of hormones from the endocrine organs, for the movement of all muscles and is in essence, the epicentre of bodily functioning, this is the most important single test that we could perform,” he says.

Hormonal TestingHormone testing

When hormone levels wane, a gamut of problems can occur, tells Safah. “The skin thins, sleep is impaired and joints may ache in addition to the brain issues,” he says therefore having optimal levels allows for easier function of our organs. Therefore hormone testing, he says, which includes progesterone, testosterone, oestrogen, DHEA, cortisol, melatonin, and pregnenolone is important. “Also the NeuroFocus Test or HPA Focus basically allows for a glimpse at brain chemical levels,” he says; this is more extensive and allows for a glimpse on how our body is handling stress.

What Category Are You In?

Are you are a relatively healthy female over 40?woman aged

For you, Rao recommends a complete hormones testing, an oestrogen metabolism studies with bone resorption, adrenal function analysis, sleep/wake cycle analysis, and cellular energy production studies. Further adding, Safah recommends a baseline hormone panel, neurotransmitter panel, thyroid panel and Vitamin D; all which he says are excellent yearly markers to ensure that optimal health is maintained.

Are you a female over 40 with pre-existing conditions?

There are recommendable tests.One is a study of cellular metabolism to understand how efficiently skeletal muscle cells are processing fat, protein and carbohydrates from your dietary consumption.Next is a nutrigenomic test that looks at inherited genetic mutations which if you have, can be managed with dietary changes and supplements. And in the case of obesity or diabetes, advanced testing for heart and bone health should also be done.
– Sam Rao, Director at XY Clinics and CEO at Diagnostika Molecular Labs

And if you have been unhealthy for a while, Safah also suggests a neurotransmitter panel with cortisol and DHEA (HPA Focus) so that overall depletions can be addressed. “It’s easy to advise an overweight patient to diet and exercise but if the neurotransmitters are depleted, it is hard for the patient to be motivated to make these changes.”

Are You a Healthy Male Over 40?man 50

The daunting statistic, says Rao, is that more than 50 percent of men who suffer from heart attacks and strokes don’t have visible symptoms and even their doctors consider them to be healthy until the event.

All men over age 40 and above should undergo advanced tests for silent cardiovascular risk factors and for sudden death.Many high functioning males have excellent ratios between their neurotransmitters however they are quite depleted.In essence, a neurotransmitter panel can allow for an indication of these depletions.
– Guillaume Safah, Canadian Registered Clinical Nutritionist Consultant and CEO at The Anti-ageing Compounding Pharmacy

Are you a male over 40 with pre-existing conditions?

The more body fat that one has and the more he weighs, the more likely he is to develop certain diseases such as coronary heart disease, high blood pressure, type 2 diabetes, gallstones, breathing problems and certain cancers, explains Dr. Ahmed.

The glucose and insulin tests should be followed by metabolic function analysis and certainly a comprehensive digestive analysis should be done along with micro-nutrient imbalance study to determine the levels of vitamins, minerals, fatty and amino acids.The idea is to gather enough information at cellular level to provide a plan to help reverse the condition.
– Sam Rao, Director at XY Clinics and CEO at Diagnostika Molecular Labs

Tests At A Glance

  • Haemogram

This simple test provides valuable information about the patient’s state of health.

  • Fasting Blood Sugar

Symptoms of type 1 diabetes often appear suddenly and are often the reason for checking blood sugar levels.

  • Liver Function Test

Liver function tests (LFTs) measure various chemicals in the blood made by the liver. An abnormal result indicates a problem with the liver.

  • Kidney Function Test

These common lab tests are used to evaluate how well the kidneys are working.

  • Lipid Profile

The test is used to assess your risk of developing cardiovascular disease.

  • Uric Acid

This measures the amount of uric acid in the blood as high levels can cause solid crystals to form within joints, known as gout.

Screenings At Every Age

  • Pre-Marital Screening

Before getting married one should know the genetic compatibility between the couple.

  • Prenatal Screening

This includes first trimester, second trimester screening and non-invasive or invasive prenatal diagnosis to check abnormalities in fetus.

  • Newborn Screening

After 24 hours of birth of a child, the screening is done to know his metabolic/ genetic and endocrinological conditions.

  • Carrier Screening

To know the carrier status of an individual if any genetic condition exists in the family.

  • Cancer Genetic Screening

To know the risk of hereditary breast, ovarian, and colon cancers.

  • Risk Assessment Test

To evaluate the risk of developing certain conditions in future, like hypertension, diabetics, and heart conditions.

  • Sexually Transmitted Disease Screening

To screen for STDs that include Chlamydia and Gonorrhoea in addition to Cytology and HPV genotyping can reduce the risk of cervical cancer.

  • Food Intolerance Test

Food intolerance and food allergies are becoming an increasing problem for many people around the world with an estimated 45 percent of the world suffering from some form of food related illness. Testing can provide information on specific allergy or intolerance a person is suffering.

Women Through The Decades

Women of different ages

30s

Osteoporosis

According to Dr. Anna Sepiolo, Obstetrician Gynaecologist and Board Certified in American Academy of Anti-Ageing and Regenerative Medicine, risk factors for osteoporosis include hormonal deficiencies, presence of fibroids, endometriosis, breast cysts, having a thin, small frame, family history of osteoporosis, eating disorders history, smoking, excessive alcohol/caffeine, sugar, salt intake, sedentary lifestyle, presence of chronic medical condition or even the use of several medications.

Doc’s Advice “If you are in the high risk group, be sure to regularly check and correct your hormone levels and nutritional status, and periodically perform a Dexa Scan which is a bone density scan.”

Stress

This is also a hugely stressful multi-tasking decade and Dr. Sepiolo tells that elevated cortisol levels are released during stressful situations and over time, can make you age quickly with symptoms ranging from gray hair, wrinkles, memory problems leading to fatigue and high blood pressure.

Doc’s Advice “The good news is that cortisol levels can be accurately measured by a saliva cortisol test.”

40s 

Perimenopause

At least 50 percent of women hit perimenopause in this decade and at this time, the level of oestrogen rises and falls unevenly and progesterone levels also decrease significantly; both which can cause oestrogen dominance. “This can result in the presence of fibroids, fibrocystic breast disease and breast cancer,” she says.

Doc’s Advice “Carefully assess, measure and correct level of nutrients, hormones, toxic elements, oxidative stress levels, gut health and fatigue.”

Breast CancerBreast Cancer

For women in their thirties, the risk of being diagnosed with breast cancer is 1 in 227 while women in their forties, this risk jumps to 1 in 68, explains Dr. Sepiolo.

Doc’s Advice “Many women begin mammograms at age 40 and have them every one to two years,” she says as a mammogram and breast scan have been shown in studies to decrease breast cancer risk even in high-risk women. Also the early detection of cervical cancer is crucial for successful treatment and is estimated to prevent up to 80 percent of cervical cancer. “The gold standard screening is to perform a Pap smear and HPV test.”

Diabetes

A woman diagnosed with diabetes at age 40 may lose an estimated 14 years from her life, according to a study in the Journal of the American Medical Association.

Doc’s Advice Dr. Sepiolo says that basic lab work should include sugar and lipids to rule out pre-diabetes.

50s

Ovarian Cancer

This is the fourth most common form of cancer among woman and largely affects post-menopausal woman with 90 percent of cases occurring over the age of 45. “Symptoms of ovarian cancer often mimic those of many other more-common conditions, including digestive problems,” says Dr. Sepiolo.

Doc’s Advice A pelvic examination as well as pelvic scan can help screen women in high risk categories.

Menopause

The goals of managing menopausal symptoms are not only alleviating symptoms but also prevent disease such as osteoporosis, cardiovascular disease and cognitive decline.

Doc’s Advice “Now it is important to measure and correct all of the hormonal deficiency, nutrient deficiency, as well as the toxicity level assessment.”

60s

In the sixties, the risk of certain disease increases, says Dr. Sepiolo, some of which include arthritis, diabetes type 2, Alzheimer’s disease, heart disease/failure, Parkinson’s disease and cancer.

Doc’s Advice “At this stage, the most important single screening test is coronary calcium score (CAC) that will be able to rule out heart disease in 10 minutes.”

Once-In-A-Lifetime Tests

The next step, tells Dr. Ahmed, is to identify the diseases exist in the family to know the risk of developing such conditions in future.

  • First Trimester ScreeningPregnancy testing

This combines a maternal blood screening test with an ultrasound evaluation of the fetus to identify risk for specific chromosomal abnormalities, including Down Syndrome. Also a portion of the test can assist in identifying other significant foetal abnormalities.

  • Second Trimester Screening

This measures the level of alpha-fetoprotein, a protein produced by the fetus and abnormal levels indicate the possibility (but not existence) of Down syndrome or a neural tube defect such as spina bifida, which can then be confirmed by ultrasound or amniocentesis.

  • Non-Invasive Prenatal Diagnosis

NIPD is a new type of genetic test that screens for birth defects and inherited diseases and seems to be much more accurate than similar screening tests.

  • Breast Cancer Genetic Test

There are the two major identified causes of inherited breast cancer, with mutations in either gene conferring up to 80 to 90 percent lifetime risk of breast cancer in carrier females. Mutations in BRCA1 account for approximately 45 percent of familial breast cancer and 90 percent of inherited breast/ovarian cancer, whereas mutations in BRCA2 account for a comparable percentage of inherited breast cancer cases.

  • DNA Molecular Diagnosis

This identifies changes in chromosomes, genes, or proteins and the results can confirm or rule out a suspected genetic condition or help determine a person’s chance of developing or passing on a genetic disorder.

The Executive Package

Eternity Medicine Institute offers a preventive screening program designed to present a comprehensive health map across the full medical spectrum.

Whether seemingly healthy or not, the battery of tests we carry out allow us to see with great clarity just where a person is requiring improvements in their health and what can be done about it. While there are no separate tests for healthy or unhealthy and initially it is all the same battery of tests for everyone, in the future, as these patients return for follow up, we may be testing for specific things relating to their specific health concerns that were spotted in the original screening.
Dr. Graham Simpson, Chief Medical Officer and Co-Founder of Eternity Medicine Institute

Eternity’s own LHAMP software plays a major role in the health management process and gives uniformity to the health management process. It involves:

  • Measuring, which lists all the test results divided up by section; for example, nutritional health, cardiovascular health, hormone balance, and so forth.
  • Mentoring, in which the Eternity physician lists the health goals and the treatment and is reviewed by the physician and patient each time they meet.
  • Monitoring, whereby every time a patient comes in for further testing, he/she will be monitored for various health improvements as per the goals set out in the mentoring section.

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